Innovation & Excellence

Leading Innovation in Precision Genomics

At Rophevac, our Research & Development is at the heart of everything we do. We are committed to pioneering innovative genomic solutions that transform healthcare and improve patient outcomes across India and globally.

Precision Medicine

Transforming healthcare through genomics and personalized medicine approaches

Precision Medicine Overview

Transforming healthcare through genomics and personalized medicine approaches based on individual genetic profiles.

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Transformative Science

Pioneering breakthrough technologies in genomics and molecular biology

Next-Generation Sequencing (NGS)

Comprehensive genomic analysis using whole genome sequencing, exome sequencing, and targeted sequencing approaches.

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Single-Cell Genomics

Cell-type specific analysis revealing tumor heterogeneity, immune profiling, and disease mechanisms at single-cell resolution.

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Epigenomics

DNA methylation and chromatin accessibility analysis for cancer classification, biomarker discovery, and gene regulation studies.

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Proteomics & Metabolomics

Protein expression profiling and metabolic pathway analysis for functional validation and biomarker discovery.

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Liquid Biopsy Technologies

Non-invasive cancer detection and monitoring using circulating tumor DNA, CTCs, and extracellular vesicles.

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Functional Genomics

CRISPR/Cas9 technology, high-throughput screening, and organoid models for target validation and disease modeling.

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Spatial Genomics & Transcriptomics

Gene expression and protein localization in tissue context for tumor microenvironment and disease progression studies.

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Data Science & AI

Harnessing artificial intelligence and machine learning for genomic insights

AI in Target Discovery & Validation

Machine learning on multi-omic datasets for target identification, protein structure prediction, and in silico validation.

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AI-Powered Variant Interpretation

Automated variant classification using VarMiner and OncoMiner platforms with ACMG/AMP guidelines.

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AI in Biomarker Discovery

Multi-omic integration and predictive biomarkers for treatment response and disease progression.

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Digital Pathology & AI

AI-powered image analysis with quantitative continuous scoring for biomarker assessment and tissue analysis.

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AI in Clinical Trial Optimization

Patient recruitment, adaptive trial designs, and real-time monitoring using artificial intelligence.

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Drug Response Prediction

Pharmacogenomics and cancer treatment selection using AI-driven molecular profiling.

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Natural Language Processing in Genomics

Scientific literature mining and clinical note analysis for evidence extraction and phenotype identification.

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AI/ML Infrastructure

Unified data platform, cloud computing, machine learning platforms, and bioinformatics tools.

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AI Ethics & Governance

Responsible AI principles, data privacy, and model validation ensuring transparency and fairness.

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Clinical Innovation

Accelerating translation from lab to clinic

Clinical Innovation Overview

Accelerating translation from lab to clinic through biomarker-driven studies and diagnostic development.

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Technologies

Advanced platforms and tools driving discovery

Sequencing Technologies

Advanced sequencing platforms including Illumina NovaSeq, NextSeq, Oxford Nanopore, and PacBio.

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Molecular Profiling Technologies

Digital PCR, qPCR, microarray platforms, and mass spectrometry for comprehensive molecular analysis.

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Imaging & Analysis Technologies

Flow cytometry, digital pathology, and FISH for immunophenotyping and chromosomal analysis.

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Bioinformatics Infrastructure

High-performance computing, cloud computing, and petabyte-scale data storage for genomic analysis.

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Proprietary Platforms

VarMiner, OncoMiner, and BioBank Repository for variant interpretation and sample management.

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Therapeutics

Next-generation therapeutic approaches based on genomic insights

Antisense Oligonucleotides (ASOs)

Synthetic DNA/RNA molecules for gene expression modulation in rare diseases and cancer.

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mRNA Therapeutics

Delivering functional mRNA for protein replacement therapy, vaccines, and regenerative medicine.

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Gene Therapy

Viral and non-viral delivery systems for inherited retinal diseases, hemophilia, and genetic disorders.

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Gene Editing

CRISPR/Cas systems including base editors and prime editors for ex vivo and in vivo gene correction.

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Cell & Gene Therapy

CAR-T cell therapy, stem cell therapy, and therapeutic gene editing for cancer and regenerative medicine.

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Oncolytic Viruses

Viruses that selectively infect and kill cancer cells while activating the immune system.

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RNA Interference (RNAi)

siRNA therapeutics for gene silencing in hereditary diseases and metabolic disorders.

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Strategic Centres

Global network of innovation hubs and research facilities

Chennai R&D Headquarters

Global R&D headquarters with CAP-accredited laboratory and comprehensive genomics capabilities.

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Bangalore Bioinformatics & AI Centre

AI and machine learning centre with high-performance computing and data science capabilities.

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Mumbai Clinical Research Centre

Clinical trials, regulatory affairs, and pharmacogenomics research facility.

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International Collaborations

Partnerships with leading institutions in USA, UK, and Europe for joint research and technology transfer.

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Centres of Excellence

Specialized centres for cancer genomics, rare diseases, infectious diseases, and population genomics.

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About Rophevac R&D

Rophevac's R&D operations are focused on advancing genetic testing technologies, developing precision medicine solutions, and creating next-generation diagnostic tools that enable early disease detection, accurate diagnosis, and personalized treatment strategies.

200+

Scientific Publications

50+

Patents Filed

500K+

Tests Performed Annually

20-25%

Revenue in R&D